Is Prozac hard on your stomach?
The large study shows that people taking selective serotonin reuptake inhibitors (SSRIs) — such as Prozac, Zoloft, and Paxil — were nearly four times as likely to be hospitalized with stomach or intestinal bleeding than people not taking one of these antidepressants.
How do I avoid GI upset with Prozac?
Consider these strategies:
- Take your antidepressant with food, unless otherwise directed.
- Eat smaller, more-frequent meals.
- Suck on sugarless hard candy.
- Drink plenty of fluids, such as cool water.
- Talk to your doctor about a dosage change or a slow-release form of the medication.
Why do SSRIs cause stomach problems?
Nausea and vomiting are caused by stimulation of serotonin 3 receptors located at the hypothalamus and the brainstem. Effects on the GI tract are mediated stimulation of serotonin 3 and 4 receptors. This stimulation can lead to increased GI motility, GI cramps.
Do Prozac side effects go away?
Mild side effects of Prozac typically go away within a few weeks of starting the medication as your body adjusts, but some side effects, including weight gain, sexual side effects, tremors, and suicidal thoughts and behaviors may continue for the duration of the use of the medication.
Do antidepressants cause gastritis?
There is also evidence that SSRI use increases gastric acidity, promoting gastritis and peptic ulcers and associated gastrointestinal (GI) bleeding (Andrade and Sharma 2016).
Can antidepressants give you stomach problems?
With antidepressants, “the most common side effect is [gastrointestinal] upset, such as nausea, vomiting, or diarrhea,” Dr. McCutcheon said. “Diarrhea leads people to become noncompliant pretty quickly.” Instead of quitting your medications, call your doctor.
Why do antidepressants make my stomach hurt?
When serotonin levels increase under the influence of SSRIs, they stimulate serotonin receptors in the GI tract as well as the brain. The combined stimulatory effect—on both the GI tract and CNS—can trigger such side effects as: Diarrhea. Loss of appetite (anorexia)
Can fluoxetine cause indigestion?
SSRIs and SNRIs Common side effects of selective serotonin reuptake inhibitors (SSRIs) and serotonin-noradrenaline reuptake inhibitors (SNRIs) can include: feeling agitated, shaky or anxious. feeling and being sick. indigestion and stomach aches.
Which antidepressant is easiest on the stomach?
Escitalopram and sertraline were shown to be the least tolerated antidepressants on the gastrointestinal tract, being associated with all the considered SEs with the exception of constipation and increased appetite, while mirtazapine was shown to be the antidepressant with fewer side effects on the gut, being only …
Do antidepressants damage your gut?
Antidepressants reduced richness and increased beta diversity of gut bacteria, compared to controls. At the genus level, antidepressants reduced abundances of Ruminococcus, Adlercreutzia, and an unclassified Alphaproteobacteria.
How long do initial side effects of Prozac last?
You can feel drowsy in the first few days of taking fluoxetine. However, it should get better after the first week or two. You may become more anxious, or it may make you irritable. This should settle after a couple of weeks.
Can antidepressants cause gastritis?