What is the drug tibolone used for?

What is the drug tibolone used for?

What is the drug tibolone used for?

About tibolone Tibolone helps to restore the balance of female hormones in women who have a lack of oestrogen; it helps to ease symptoms such as hot flushes and night sweats. You will only be prescribed it if these symptoms seriously interfere with your daily life.

Why is tibolone banned in the US?

In January, the firm was forced to terminate its LIFT study of Livial – designed to investigate the effect of tibolone on new vertebral fractures in elderly osteoporosis patients – after an interim analysis showed that the drug increased the incidence of stroke.

What are the side effects of taking tibolone?

Side-effects may include headache, dizziness, nausea, abdominal pain, swollen feet and itching. Breast tenderness is uncommon. Slight bleeding or spotting may commonly occur initially but tends to subside after a few months.

Does tibolone cause weight gain?

Overall tibolone was well tolerated and climacteric symptoms were relieved within 3-5 weeks. The major side effect was weight gain and/or a tendency to bloating and oedema which occurred in 11.28% of our women.

Is tibolone a good HRT?

Tibolone can serve as an appropriate choice for HRT as it has low rates of vaginal bleeding/ spotting episodes and high acceptance rate in postmenopausal women.

How long can I take tibolone for?

For the treatment of postmenopausal symptoms, Tibolone should only be initiated for symptoms that adversely affect quality of life. In all cases, a careful appraisal of the risks and benefits should be undertaken at least annually and Tibolone should only be continued as long as the benefit outweighs the risk.

How safe is tibolone?

Stroke. The LIFT study identified a significantly (2·2-times) increased risk of stroke, mostly ischaemic, in tibolone users; risk increased from the first year of treatment. Baseline risk of stroke is strongly age-dependent, and so the absolute risk with tibolone increases with older age.

Will tibolone help me lose weight?

Compared with placebo, tibolone significantly increased fat-free mass by 0.85 kg (P= 0.003) and total body water by 0.78 liter (P = 0.001). No significant difference was observed on the fat mass parameter (P = 0.16).

Does tibolone help you sleep?

In Menopause Management: Hormone Replacement Therapy (HRT) – Tibolone (Livial or Xyvion): Testosterone – Symptoms It Assists In Preventing the JH elaborate on: “It can help to improve mood and sleep quality, decrease hot flushes and improve general wellbeing”.

Is tibolone any good?

Moderate-quality evidence suggests that tibolone is more effective than placebo but less effective than HT in reducing menopausal vasomotor symptoms, and that tibolone is associated with a higher rate of unscheduled bleeding than placebo but with a lower rate than HT.