What is Metanephric Blastema?

What is Metanephric Blastema?

What is Metanephric Blastema?

The metanephrogenic blastema or metanephric blastema (or metanephric mesenchyme, or metanephric mesoderm) is one of the two embryological structures that give rise to the kidney, the other being the ureteric bud.

Who has metanephric kidney?

metanephros, permanent kidney in reptiles, birds, and mammals, developing by the 10th week in human embryos from the lower part of the Wolffian duct, and replacing the embryonic structure called the mesonephros.

What are nephrons derived from?

The ureteric bud, which forms the collecting ducts, is derived from the nephric or Wolffian duct. Development of the metanephric kidney begins when the ureteric bud invades the MM and mesenchymal cells near the bud are converted to epithelium, which then goes on to form the nephron.

Where does Metanephric Blastema come from?

The metanephros develops from the ureteric bud and the metanephrogenic blastema. The ureteric bud forms the primitive ureter of the metanephric kidney and dilates at its upper end to become the renal pelvis, enveloped by the metanephrogenic cap.

What is nephrogenic blastema?

Persistent metanephric blastemas after 36 weeks of gestational age are called nephrogenic rests. They are associated with nephroblastomatosis and are a precursor lesion to Wilms tumors.

What is the difference between mesonephric kidney and metanephric kidney?

The key difference between pronephric mesonephric and metanephric kidney is that pronephric kidney is the earliest nephric stage while mesonephric kidney develops between the sixth and tenth week and metanephric kidney develops and functions between fifth to the twelfth week in the embryonic development stage.

What is metanephric mesenchyme?

The metanephric mesenchyme (MM) is one of the two embryonic structures that give rise to the kidney. The other structure is the ureteric bud. MM is comprised of mesenchymal cells situated adjacent to the tips of the branching ureteric bud. These cells form the nephrons.