What does eccentric hypertrophy mean?
Medical Definition of eccentric hypertrophy : hypertrophy of the wall of a hollow organ and especially the heart with dilatation of its cavity.
What does it mean when a ventricle is compliant?
In a. general sense, the term ventricular compliance. refers to the distensibility of the relaxed. ventricle, defined in terms of its diastolic. pressure-volume relationship.
What is the difference between eccentric and concentric hypertrophy?
Concentric hypertrophy is associated with increased left ventricular wall thickness whereas eccentric hypertrophy is characterized by dilatation of the left ventricular chamber; however, there occurs a general increase in the overall size of cardiomyocytes under both conditions.
Is eccentric hypertrophy the same as dilated cardiomyopathy?
Dilated cardiomyopathy (DCM) is characterized by dilatation of the ventricles, elevated filling pressures, eccentric myocyte hypertrophy, impaired diastolic filling, and systolic dysfunction (Beltrami et al., 1995). DCM is often caused by ischemic heart disease or long-term hypertension (Wexler et al., 2009).
Is eccentric hypertrophy normal?
Eccentric hypertrophy is generally regarded as healthy, or physiologic hypertrophy and is often termed “athlete’s heart.” It is the normal response to healthy exercise or pregnancy, which results in an increase in the heart’s muscle mass and pumping ability.
What causes eccentric hypertrophy?
Eccentric left ventricular hypertrophy is induced by an increased filling pressure of the left ventricle, otherwise known as diastolic overload, which represents the underlying mechanism for volumetric or diastolic overload in patients with regurgitant valve lesions such as aortic or mitral regurgitation as well as in …
What causes increased ventricular compliance?
In a disease state such as dilated cardiomyopathy, the ventricle becomes very dilated without appreciable thickening of the wall. This dilated ventricle will have increased compliance as shown in the figure; therefore, although the EDV may be very high, the EDP may not be greatly elevated.
How does compliance affect ventricular function?
Typically in RCM, ventricular filling is completed in early diastole with little or no filling in late diastole as a result of increased myocardial stiffness with decreased compliance. This results in a marked ventricular pressure rise with small changes in volume.
Is eccentric hypertrophy good?
Is eccentric hypertrophy bad?
When does eccentric hypertrophy occur?
Sometimes the chamber radius is increased and the wall thickness is increased moderately – this is termed eccentric hypertrophy – and can occur when there is both volume and pressure overload.