What does an elevated CK-MB indicate?
If you have higher than normal CK-MB enzymes, it may mean you have an inflammation of the heart muscle or are having or recently had a heart attack. If you have higher than normal CK-BB enzymes, it may mean you have had a stroke or brain injury.
What conditions cause elevated CK?
Other causes of increased creatine kinase (CK) levels
- Hormonal (endocrine) disorders, such as thyroid disease, Addison’s disease or Cushing’s syndrome.
- Prolonged surgeries.
- Seizures.
- Infections (viral, bacterial, fungal or parasitic).
- Connective tissue disorders, such as lupus and rheumatoid arthritis.
- Celiac disease.
What causes elevated CPK MB?
Elevated CK-MB fraction is seen in prostatic carcinoma and other underlying malignancy, such as breast cancer. Certain drugs that can increase CPK measurements include amphotericin B, certain anesthetics, statins, fibrates, dexamethasone, alcohol, and cocaine.
Are CK levels elevated in myasthenia gravis?
Abstract. Cases of myasthenia gravis with inflammatory myopathy usually show elevated creatine kinase (CK) levels.
What is the significance of elevated CK-MB and TNL?
In conclusion, levels of CK-MB and Tn-I in patients with heart failure (particularly class III–IV) were found to be significantly increased, showing a relationship between the clinical severity of the disease and elevation of myocardial enzymes (CK-MB and Tn-I) in CHF.
What are the differential diagnosis of myasthenia gravis?
Differential diagnosis includes congenital myasthenic syndromes, Lambert Eaton syndrome, botulism, organophosphate intoxication, mitochondrial disorders involving progressive external ophthalmoplegia, acute inflammatory demyelinating polyradiculoneuropathy (AIDP), motor neuron disease, and brainstem ischemia.
What is the difference between Lambert Eaton syndrome and myasthenia gravis?
The difference between LEMS and myasthenia gravis (MG) This is very similar to myasthenia gravis, however the target of the attack is different in MG as the acetylcholine receptor on the nerve is affected, whereas in LEMS it’s the voltage-gated calcium channel on the nerve.