What are the symptoms of CVID?

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What are the symptoms of common variable immunodeficiency (CVID)?

Breathing problems.
Chronic cough.
Diarrhea that causes weight loss.
Ear infections.
Frequent sinus infections.
Recurring lung infections, including pneumonia.

Is CVID considered immunocompromised?

The World Health Organization (WHO) recognizes more than 400 primary immunodeficiencies ranging from relatively common to quite rare. CVID is one of the most prevalent of the symptomatic primary immunodeficiencies and manifests a wide variability of symptoms and range of severity.

What is the survival rate for CVID?

The large study of 248 patients with CVID [1] estimated that the post-diagnosis 20-years survival rate were 64 and 67% for males and females, respectively, compared with similar ages in the general population (92% for males and 94% for females).

Can CVID be treated?

CVID is treated with intravenous immunoglobulin infusions or subcutaneous (under the skin) immunoglobulin injection to partially restore immunoglobulin levels. The immunoglobulin given by either method provides antibodies from the blood of healthy donors.

Can CVID cause fatigue?

Patients with common variable immunodeficiency (CVID) have increased fatigue compared with the general population. Fatigue is associated with lower quality of life (QoL), which is associated with higher mortality in CVID.

Can you recover from CVID?

Coronavirus Recovery Rates On average about 98.2% of known COVID-19 patients in the U.S. survive, but each individual’s chance of dying from the virus will vary depending on their age, whether they have an underlying health condition and whether they are vaccinated.

Does common variable immune deficiency cause pain?

People with CVID may develop an enlarged spleen and swollen glands or lymph nodes, as well as painful swollen joints in the knee, ankle, elbow, or wrist.

Can you live a long life with CVID?

The life expectancy of CVID patients has considerably improved over the past 30 years [5, 63], from initially 12 years to currently over 50 years [3]. Reduced survival was significantly associated with age at diagnosis, lower baseline IgG, higher IgM and fewer peripheral B cells.

Does CVID cause joint pain?

Some patients with CVID who may not be receiving optimal immunoglobulin replacement therapy may also develop a painful inflammation of one or more joints. This condition is called polyarthritis. In the majority of these cases, the joint fluid does not contain bacteria.