What are the myelinating cells of the CNS?
Schwann cells make myelin in the peripheral nervous system (PNS: nerves) and oligodendrocytes in the central nervous system (CNS: brain and spinal cord).
Do oligodendrocytes Myelinate?
Oligodendrocytes are fundamental to myelin formation in the developing CNS and critical for myelin regeneration following injury including in the most common demyelinating disease multiple sclerosis (MS) [2,3].
How many types of oligodendrocytes are there?
(Bottom left) The four types of oligodendrocytes recognized by del Río-Hortega.
What is the difference between Oligodendroglia and oligodendrocyte?
Oligodendrocytes (oligodendroglia) form and maintain the myelin sheaths that surround processes of CNS neurons. Each oligodendrocyte sheathes multiple axons. Oligodendrocytes have round nuclei with condensed chromatin that stain darker than those of astrocytes and neurons, and they lack basal lamina.
Where are Unmyelinated neurons found?
Compared to myelinated neurons, unmyelinated neurons are slower in terms of conducting impulses and are found in the peripheral nervous system (especially visceral nervous system) and the gray matter of the nervous system. Synonym: non-myelinated nerve.
Why do we have Unmyelinated neurons?
Myelinated neurons are neurons whose axons are surrounded by myelin; the myelin has has an insulating effect and allows the axons to conduct neural impulses faster – but at some metabolic cost, so neurons are not myelinated unless there is a significant advantage to they’re being able to conduct faster.
Do oligodendrocytes regenerate?
Oligodendrocytes readily regenerate and replace myelin membranes around axons in the adult mammalian central nervous system (CNS) following injury.
What is the role of the oligodendrocyte?
Oligodendrocytes are the myelinating cells of the central nervous system (CNS). They are the end product of a cell lineage which has to undergo a complex and precisely timed program of proliferation, migration, differentiation, and myelination to finally produce the insulating sheath of axons.
What are Oligodendroglia cells?
What is a oligodendrocyte cell?
What are the two main differences between Schwann and oligodendrocyte cells?
The primary difference is their location. Oligodendrocytes myelinate the central nervous system, while Schwann cells myelinate the peripheral nervous system. Oligodendrocytes are also capable of myelinating multiple axons, while Schwann cells can only myelinate one axon per cell.