How is odontogenic keratocyst diagnosed?
Diagnosis is usually radiological. However, definitive diagnosis is through biopsy. Aspirational biopsy of odontogenic keratocysts contains a greasy fluid which is pale in colour and contains keratotic squames. Protein content of cyst fluid below 4g% is diagnostic of odontogenic keratocysts.
What is the treatment of odontogenic keratocyst?
Treatment of odontogenic keratocyst (OKC) is one of the highly controversial protocols among oral and maxillofacial surgeons. Treatment modalities range from simple enucleation in the case of lesions that are less than 1 cm to extensive resection in the case of cysts that extend into the skeletal base.
How is OKC treated?
Based on extensive research, recommended treatment modalities for OKC that are known to reduce/prevent recurrence include enucleation, excision of overlying mucosa followed by application of Carnoy’s solution, marsupialization/decompression followed by cystectomy, and mandibular resection.
What causes odontogenic keratocyst?
Odontogenic keratocysts (OKCs) are generally thought to be derived from remnants of the dental lamina (rests of Seres), traumatic implantation or down growth of the basal cell layer of the surface epithelium, or reduced enamel epithelium of the dental follicle.
How is OKC diagnosed?
Diagnosis of the unilocular cyst is based on histology. The OKC is lined with a thin layer of connective tissue covered by ortho- or parakeratinized stratified squamous epithelium with columnar or cuboidal basal cells. If the cyst is infected, inflammatory cells are present.
Is OKC a cyst or tumor?
OKC is the one of the rare odontogenic cysts, which attracts many researchers due to its unique characteristics. OKC originates from the dental lamina remnants in the mandible and maxilla before odontogenesis is complete. It may also originate from the basal cells of overlying epithelium.
What is Carnoy’s solution used for?
Carnoy’s solution is used in the treatment of various aggressive cysts and tumors in the maxillofacial region as a chemical cauterizing agent. Its use has been extensively studied in case of odontogenic keratocysts. It is used in the management of unicystic ameloblastomas and ossifying fibromas.
How are odontogenic Keratocysts removed?
Odontogenic keratocysts can initially be treated with incisional biopsy and decompression by installing a polyethylene drain to allow subsequent reduction of the cystic cavity size, resulting in thickening of the capsule, which allows a later easy removal withapparently lower relapse rate (Waldron).