How is hypopituitarism managed?
The treatment of hypopituitarism includes therapies directed at the underlying disease process, and endocrine replacement therapy. The pituitary tumours may be treated with medical therapy, surgery, radiotherapy, or a combination of these modalities.
Which hormone should be replaced first in hypopituitarism?
The aim of management is usually to replace the target-hormone of hypothalamo-pituitary-endocrine gland axis with the exceptions of secondary hypogonadism when fertility is required, and growth hormone deficiency (GHD), and to safely minimise both symptoms and clinical signs.
What drugs stimulate pituitary gland?
A growth hormone receptor antagonist used to treat acromegaly….Pituitary Hormones.
| Drug | Target | Type |
|---|---|---|
| Felypressin | Vasopressin V1a receptor | target |
| Urofollitropin | Follicle-stimulating hormone receptor | target |
| Carbetocin | Oxytocin receptor | target |
| Tetracosactide | Adrenocorticotropic hormone receptor | target |
Is hydrocortisone used for hypopituitarism?
Because there is no test to assess the adequacy of the replacement, the optimal doses are not known. Most authorities recommend replacement with hydrocortisone because that is the hormone the adrenal glands make normally (hydrocortisone and cortisol are different names for the same chemical structure).
How is Hyperpituitarism treated?
Treatment options
- Medication. If a tumor is causing your hyperpituitarism then medication may be used to shrink it.
- Surgery. Surgery is performed to remove a tumor from the pituitary gland.
- Radiation. Radiation is another option if you’re unable to have surgery to remove the tumor.
Why Steroids are given in hypopituitarism?
Medications. Hormone replacement medications may include: Corticosteroids. These drugs, such as hydrocortisone (Cortef) or prednisone (Rayos), replace the adrenal hormones that aren’t being produced because of an adrenocorticotropic hormone (ACTH) deficiency.
Which is better bromocriptine or cabergoline?
Cabergoline is more effective than bromocriptine in resolution of amenorrhea/oligomenorrhea and galactorrhea, and probably increases pregnancy rate. Cabergoline leads to less adverse effects than bromocriptine.
Why is hydrocortisone given after pituitary surgery?
Hydrocortisone tablets are prescribed for all patients after pituitary surgery. Hydrocortisone is similar to cortisol, one of the body’s natural steroid hormones (chemical messengers). Without enough cortisol, you would become ill.
Is Somatropin is used for hypopituitarism?
Growth hormone. Also called somatropin (Genotropin, Humatrope, others), growth hormone is administered through an injection beneath your skin. It promotes growth, which helps produce a more normal height in children.
How often do you inject somatropin?
The usual dose is 0.06 mg per kg of body weight, given 3 times per week and injected under the skin or into a muscle. Your doctor may adjust your dose if needed.